Penile Injection for Male Enhancement

In the penile injection method, medication is injected directly into the penis’ side to induce an erection. Here, the injection dilates the penis’ arteries, thereby allowing the blood to flow in. This helps in creating an erection after around 5 to 15 minutes. The medication can induce erection even when there is no sexual arousal. The erection can last between 30 to 60 minutes or until orgasm. This method mainly helps in increasing penis girth rather than length.


This method was discovered in 1977, when a surgeon inadvertently injected Papaverine near the penile area while performing a bypass surgery. In later tests, a complete erection for around 2 hours was observed in a patient with erectile dysfunction (ED). In tests conducted later on cats, medications like Phentolamine (Regitine) were intravenously administered. In 1983, 11 men with ED tested by Dr. Brindley, a physiology professor at the Institute of Psychiatry in London, were able to have intercourse after the injection was administered.

The Medications Used for Penile Injections

After a lot of experiments with more than 40 various kinds of medications, Papaverine, Prostaglandin E1, and Phentolamine have been medically accepted for penile injection.

Papaverine Hydrochloride

This was initially the medication that was most trusted for penile injections. It helps in totally relaxing the muscle cells of the arterial wall. This causes dilation resulting in an improved blood flow in the penis. According to observers, a second administration of Papaverine traps the blood inside the penis, resulting in a well maintained erection.

Prostaglandin E1

This is a chemical that is naturally formed in the human body. This was discovered around 3 decades ago and is a potent vasodilator. The muscle cells in the penis’ arteries get relaxed, resulting in a significant erection.


This medication blocks the nerves that signal the contraction of the arterial muscle wall. Like both Papaverine and Prostaglandin, this results in the dilation of the arteries and the relaxing of muscle cells in the wall of the arteries. Phentolamine and Papaverine complement each other very well and are mostly used together for good effect. Some of the other substances used in injections are silicone, collagen, and mineral oil.


A 30-gauge ultra-fine needle should be used to administer the injection. The number of injections should not be more than 10 per month and should be spaced evenly. It is important to alternate between both sides of the penis.

Advantages of Penile Injections

1. More than 90% of the men who have used the needle say that it was painless. Very minimal bleeding or bruising is observed, as the needle hole is very small.

2. Papaverine and Phentolamine cause hardly any pain, although sometimes patients feel a dull ache for a short period of time at the base of the penis with Prostaglandin. This ache subsides in around 15 minutes.

3. This method is safe for patients who are on Coumadin, aspirin, and Persantine.

4. Men don’t have to go the clinic and can administer the injections at home

Disadvantages and Risks Associated with Penile Injections

1. This method can result in priapism, which is a sustained erection that can be quite painful. Erection can last up to 8 hours and is a medical emergency.

2. When the needle is stuck, a small bruise or scarring can occur

3. Excess usage of Papaverine can result in a skipped heartbeat. The exact dosage should be consulted with the physician

4. All the medications used are expensive

5. Excess usage of substances could lead to the penis becoming permanently disfigured

6. Some men take a lot of time in learning this technique

Please be sure to consult your personal physicial or medical expert before you plan any male enhancement procedure. Failure to do so can cause severe non-reversible medical complications.


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Posted on August 11, 2012 at 2:06 pm by admin · Permalink
In: Penis Enlargement